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Bug-Zapper: A Dose Of Radiation May Help Knock Out Malaria
11/9/07
(www.americanheart.org)Researchers used their expertise in radiation science to help a young company create weakened, harmless versions of malaria-causing parasites that, in turn, are being used to create a new type of vaccine that shows promise of being more effective than current malaria vaccines.

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Aging and Oxidative Stress
11/7/07
(news.bbc.co.uk)Oxidative stress is the unassuming name for the state in which reactive oxygen species - the free radicals of the free radical theory of aging - are present in sufficient numbers to overwhelm the body's antioxidant defenses and thus cause potentially lasting damage and degredation by reacting with important molecules in cellular machinery. If you care to head back in the archives a way, I explain some of the mechanisms in more detail in a post on the mitochondrial free radical theory of aging: where it is these reactive oxygen species come from, and how it is that they can do so much harm, leading to conditions such as atherosclerosis. A paper on the rise of oxidative stress with aging caught my eye today: Aging-Related Oxidative Stress in Healthy Humans: Oxidative stress has been reported to increase with aging; however, the scientific evidence is controversial. We therefore aimed to analyze the relationship between aging and some markers of oxidative stress. ... there was no age-related change in oxidative stress markers in subjects of < 60 years. These findings suggest that age of > 60 years may be associated with increased oxidative stress. The full PDF version of that paper is...

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Marked Brain Changes Afflict Even Senior Citizens Who Have Escaped Alzheimer's Disease
11/6/07
(www.americanheart.org)Our brains, unlike the skin covering our bodies, do not wrinkle and sag as we age. But new studies show that our brains do change structurally and functionally in ways that may underlie the memory and thinking impairments that can limit independence and quality of life for senior citizens. Neuroscientists have recently discovered that the region of the brain that stores episodic memories -- those for specific events and their context -- was less engaged in older people, particularly those who have a common variant of a particular gene. Researchers also have determined that senior citizens who suspect that their sense of direction is declining are astute observers of a newly discovered age-related mental change.

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Genome Study Charts Genetic Landscape Of Lung Cancer
11/5/07
(www.americanheart.org)An international team of scientists have announced the results of a systematic effort to map the genetic changes underlying lung cancer, the world's leading cause of cancer deaths. Comprehensive analysis of DNA from human lung tumors uncovers more than 50 common genetic abnormalities, less than half involve known cancer genes.

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Facts about Vaccines
11/4/07
Vessel-thwarting Antibody Might Help Starve Cancerous Tumors
An antibody might offer a safe and effective complement to anticancer therapies designed to starve malignant tumors by pruning the blood vessels that feed them, researchers report.
Vaccine Against Deadly Infections
While vaccines are a proven, safe and effective way to prevent certain life-threatening diseases, myths abound about vaccinations and the risks that they pose to human health. This is a sobering thought when you consider at least two million children die each year from diseases that are vaccine-preventable.
(In hopes of combating the growing scourge of antibiotic-resistant bacteria, in particular drug-resistant staph bacteria, scientists have designed a new type of vaccine that could one day be used in humans to block the onset of infection.)
Immunization has led to great advances in eradicating common childhood illnesses. Without it, infants and children would still suffer from diseases such as measles, mumps, tetanus, polio and pertussis (whooping cough).
Doctors do not know which the cause of every ear infection is and to find out they should perform a ear tap which can be painful and complicated. So, they prescribe an antibiotic for the most likely cause of the infection, but that antibiotic could be a wrong one. Lately, cephalosporins have proved to be effective in most types of ear infections.
The benefits and minimal risks associated with immunization far outweigh the disease and death that would occur without it.
(Board-Reader.com)

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