(news.bbc.co.uk)Oxidative stress is the unassuming name for the state in which reactive oxygen species - the free radicals of the free radical theory of aging - are present in sufficient numbers to overwhelm the body's antioxidant defenses and thus cause potentially lasting damage and degredation by reacting with important molecules in cellular machinery. If you care to head back in the archives a way, I explain some of the mechanisms in more detail in a post on the mitochondrial free radical theory of aging: where it is these reactive oxygen species come from, and how it is that they can do so much harm, leading to conditions such as atherosclerosis. A paper on the rise of oxidative stress with aging caught my eye today: Aging-Related Oxidative Stress in Healthy Humans: Oxidative stress has been reported to increase with aging; however, the scientific evidence is controversial. We therefore aimed to analyze the relationship between aging and some markers of oxidative stress. ... there was no age-related change in oxidative stress markers in subjects of < 60 years. These findings suggest that age of > 60 years may be associated with increased oxidative stress. The full PDF version of that paper is...

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